Immune cell defects and humoral immune defect HSV

What genital herpes immunology? The prevention and cure of genital herpes what help? Beijing changhong hospital urology experts, patients with the introduction of HSV reaction how will directly affect the body if the severity of the illness and infection, latent infections develop and maintain and HSV recurrence frequency. If patients have the cellular immune defects and humoral immune defects of HSV infection are serious, illness that antibodies and cell mediated mediated immune response to HSV patients is very important. The animal experiment proves, T lymphocytes, NK cells and macrophages in the prevention of HSV diffusion in plays the leading role, antibody is to reduce the amount of virus in the nerve tissue
In given conditions, the specificity of polyclonal antibody HSV, HSV monoclonal antibodies, are already contact HSV antigen lymphocytes and in view of the viral antigens cloning T cell have protection from nervous system diseases or ganglion latent infections. The host immune response in HSV pathogenesis may also plays a role, HSV antigen cellular immune response involves DuoZhong cells, such as natural killer cells and macrophages, T lymphocyte subsets and by these cells produce a lymphoid factor. To animal passive input had contact with HSV antigen lymphocytes, and garnish with virus attack, animals can be protected without morbidity. Maximum protection need to activate DuoZhong T cells subsets.
University of Denver marriage and family research center director Howard? MaErKe mann and Scott? Stanley since 1996, he began to the Denver area 306 couples to carry on the long-term research, trying to find out the play together with a happy marriage and relationships. They finally chose to marriage in 197 in the second year of the husband and wife of the questionnaire for analysis.
Psychologists MaErKe mann says, play and a happy marriage significant and close relationship between husband and wife, two people together have fun, the more time the happier marriage. And play together for men is more important. Survey found that men were more like his own "the other half" called "best friend". And watch TV, Internet, such as the individual activities, the happiness in marriage nothing.
Recently the United States "journal archives of sexual behavior KanWen points out, in the long run, hugging and kissing intimacy for men and way more important, especially in the marriage of more than 10 years of family, intimacy can bring man more happiness.
Indiana university institute of gold and researchers in the United States, Germany, Spain, Japan and Brazil's 1000 couples to carry on the investigation, they live together in a year's time-51 years, half of them live in between 25 years. Respondents age 40 to 70 years old in between. The researchers examined in the past month kiss and embrace between husband and wife, touch and sex, and the number of the happiness of marriage they test. The results found that often kiss and embrace male happiness considerably higher, and women, not much difference. However, women feel happy times greater effect on sex.
Beijing changhong hospital urology experts said, through to the herpes damage to research shows that, CD8T lymphocytes participate in the control of infection, the newborn, the infection HSV gamma-interferon expression is significantly delayed. Interferon may have direct antiviral effect or may activate other nonspecific effect cells.
Primary infection, the use of radioimmunoassay and antibody poisoning experiment, rely on cells in symptoms can be detected 4 days HSV IgG antibodies. And not rely on the complement and antibodies and CF antibody usually symptoms 2-3 weeks after the measure. Infection can be measured the early to HSV specific IgM IgM for 8 weeks, but in the latent infections and asymptomatic infections is not measured in IgM. Usually, asymptomatic infected with HIV and the recurrence of herpes will HSV IgG, or IgA antibody drops IgM no difference degree.
Recently, the detection antibody IgG subtypes of the early of genital herpes IgG infection, again hair also can be detected, and IgG2, 3, 4, early in the infection from but not detection. In addition, some interesting is IgG4 report, women than men are high frequency detection, but some chased try this test but get different results. And by that method can be detected a blot. The specific protein antibody, HSV containing 5-6 kinds of glycoprotein, including immune source sex protein, HSV-1 have 23, HSV-Ⅱ, there are 10-15, but for this kind of protein antibody in clinical meaning is unclear.